Use and applications of nucleic acid probes in the clinical laboratory.

@article{Mifflin1989UseAA,
  title={Use and applications of nucleic acid probes in the clinical laboratory.},
  author={Theodore E. Mifflin},
  journal={Clinical chemistry},
  year={1989},
  volume={35 9},
  pages={
          1819-25
        }
}
The use and availability of nucleic acid probes are significantly greater than they were three to five years ago. This increased utilization has resulted because of numerous changes in molecular genetic procedures. First, the sources of probes have shifted from cloned genomic and cDNA fragments to single-strand oligonucleotides and RNA or "riboprobes." These newer probes offer defined composition and capability to create separate sense and anti-sense strands. Second, an increased variety of… CONTINUE READING

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