Use and abuse of mathematical models: an illustration from the 2001 foot and mouth disease epidemic in the United Kingdom.

@article{Kitching2006UseAA,
  title={Use and abuse of mathematical models: an illustration from the 2001 foot and mouth disease epidemic in the United Kingdom.},
  author={Richard Paul Kitching and Michael V. Thrusfield and Nick M. Taylor},
  journal={Revue scientifique et technique},
  year={2006},
  volume={25 1},
  pages={
          293-311
        }
}
Foot and mouth disease (FMD) is a major threat, not only to countries whose economies rely on agricultural exports, but also to industrialised countries that maintain a healthy domestic livestock industry by eliminating major infectious diseases from their livestock populations. Traditional methods of controlling diseases such as FMD require the rapid detection and slaughter of infected animals, and any susceptible animals with which they may have been in contact, either directly or indirectly… 

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References

SHOWING 1-10 OF 90 REFERENCES

Foot‐and‐mouth disease in the UK: What should we do next time?

Retrospective analyses suggest that the subsequent course of the epidemic was consistent with a beneficial impact of the contiguous cull and that it would have been difficult to achieve a better outcome using reactive vaccination, which would have required very large-scale vaccination programmes to have been implemented quickly.

Transmission intensity and impact of control policies on the foot and mouth epidemic in Great Britain

It is shown that the species mix, animal numbers and the number of distinct land parcels in a farm are central to explaining regional variation in transmission intensity, and that extended culling programmes were essential for controlling the epidemic to the extent achieved.

Descriptive epidemiology of the 2001 foot-and-mouth disease epidemic in Great Britain: the first five months

The epidemic was large as a result of a combination of events, including a delay in the diagnosis of the index case, the movement of infected sheep to market before FMD was first diagnosed, and the time of year.

The UK foot-and-mouth disease outbreak — the aftermath

Improved understanding is needed of where, how and why control measures initially failed in 2001 and how new policies should be implemented to receive the full confidence of scientists, veterinarians and the general public.

The economics of foot and mouth disease.

The published studies indicate that where FMD eradication is feasible, this is the least-cost policy option, even allowing for the costs of prevention, emergency preparedness and the risk of outbreaks.

Modelling vaccination strategies against foot-and-mouth disease

A reactive strategy, ‘predictive’ vaccination, is explored, which can reduce markedly the long tail that characterizes many FMD epidemics and have broader implications for the control of human and livestock infectious diseases in heterogeneous spatial landscapes.

The Foot-and-Mouth Epidemic in Great Britain: Pattern of Spread and Impact of Interventions

An analysis of the current foot-and-mouth disease epidemic in Great Britain over the first 2 months of the spread of the virus suggests that more drastic action, such as “ring” culling or vaccination around infection foci, is necessary for more rapid control.

Predictive spatial modelling of alternative control strategies for the foot-and-mouth disease epidemic in Great Britain, 2001

A spatial simulation model of foot-and-mouth disease was used in March and early April 2001 to evaluate alternative control policies for the 2001 epidemic in Great Britain, producing an epidemic involving over 6000 farms by October 2001, with no prospect of immediate eradication.

Epidemiology: Foot-and-mouth disease under control in the UK

It is concluded that foot-and-mouth disease has now been brought under control, but it will be important to contain rapidly any new outbreaks in previously unaffected areas.

The epidemiology of foot-and-mouth disease: implications for New Zealand.

  • R. Sanson
  • Biology, Medicine
    New Zealand veterinary journal
  • 1994
This paper attempts to draw on overseas historical outbreak experiences and research findings to gain insights into the epidemiology of foot-and-mouth disease as it would relate to New Zealand.
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