Usage of TCRAV and TCRBV gene families in human fetal and adult TCR rearrangements

@article{Raaphorst1994UsageOT,
  title={Usage of TCRAV and TCRBV gene families in human fetal and adult TCR rearrangements},
  author={Frank M. Raaphorst and J A van den Bergen and Ren{\'e}e Langlios van den Bergh and Maarten van der Keur and Ronald R. de Krijger and Jan G Bruining and Maarten J. D. van Tol and J. P. Vossen and Peter J. van den Elsen},
  journal={Immunogenetics},
  year={1994},
  volume={39},
  pages={343-350}
}
We have investigated fetal and adult T-cell receptor (TCR) A and B V-gene repertoires both by fluorescence-activated cell sorter (FACS) analysis with the avialable TCR V region-specific mAbs and by the polymerase chain reaction (PRC) with TRC V gene family-specific oligonucleotides. Among the low number of CD3+ T cells, most of the TRC V region tested for… CONTINUE READING