Ursolic acid suppresses leptin-induced cell proliferation in rat vascular smooth muscle cells.

Abstract

Accumulating lines of evidence indicate that high leptin levels are associated with adverse cardiovascular health in obese individuals. Proatherogenic effects of leptin include endothelial cell activation and vascular smooth muscle cell proliferation and migration. Ursolic acid (UA) has been reported to exhibit multiple biological effects including… (More)
DOI: 10.1139/cjpp-2016-0398

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