Ursolic acid in cancer prevention and treatment: molecular targets, pharmacokinetics and clinical studies.

@article{Shanmugam2013UrsolicAI,
  title={Ursolic acid in cancer prevention and treatment: molecular targets, pharmacokinetics and clinical studies.},
  author={Muthu Kumaraswamy Shanmugam and Xiaoyun Dai and Alan Prem Kumar and Benny Kwong Huat Tan and Gautam Sethi and Anupam Bishayee},
  journal={Biochemical pharmacology},
  year={2013},
  volume={85 11},
  pages={1579-87}
}
Discovery of bioactive molecules and elucidation of their molecular mechanisms open up an enormous opportunity for the development of improved therapy for different inflammatory diseases, including cancer. Triterpenoids isolated several decades ago from various medicinal plants now seem to have a prominent role in the prevention and therapy of a variety of ailments and some have already entered Phase I clinical trials. One such important and highly investigated pentacyclic triterpenoid, ursolic… CONTINUE READING
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Auxiliarydirected oxidation of ursolic acid by 'Ru'-porphyrins: chemical modulation of cytotoxicity against tumor cell lines

K Tanaka, K Mazumder, +3 authors K. Fukase
Tetrahedron Lett 2012;53:1756-9 • 2012

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