Ursodeoxycholic acid in the treatment of cholestasis of pregnancy: a randomized, double-blind study controlled with placebo.

@article{Palma1997UrsodeoxycholicAI,
  title={Ursodeoxycholic acid in the treatment of cholestasis of pregnancy: a randomized, double-blind study controlled with placebo.},
  author={J. Palma and H. Reyes and J. Ribalta and I. Hern{\'a}ndez and L. Sandoval and R. Almuna and J. Liepins and F. Lira and M. Sedano and O. Silva and D. Toh{\'a} and J. Silva},
  journal={Journal of hepatology},
  year={1997},
  volume={27 6},
  pages={
          1022-8
        }
}
  • J. Palma, H. Reyes, +9 authors J. Silva
  • Published 1997
  • Medicine
  • Journal of hepatology
  • BACKGROUND/AIMS Intense pruritus and the risk of stillbirths and premature deliveries justify the search for an effective pharmacologic treatment of intrahepatic cholestasis of pregnancy. This study was designed to test the efficacy of ursodeoxycholic acid in maternal pruritus, the biochemical abnormalities and the outcome of pregnancy, in patients with intrahepatic cholestasis of pregnancy of early onset. METHODS Pregnant patients hospitalized in a secondary case-referral center with intense… CONTINUE READING
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