Ursodeoxycholate protects against ethanol-induced liver mitochondrial injury.

@article{Tabouy1998UrsodeoxycholatePA,
  title={Ursodeoxycholate protects against ethanol-induced liver mitochondrial injury.},
  author={L J Tabouy and A. J. Zamora and Laurence Oliva and A. M. Montet and Françoise J Beaug{\'e} and J. C. Montet},
  journal={Life sciences},
  year={1998},
  volume={63 25},
  pages={2259-70}
}
The purpose of this work was to examine whether ursodeoxycholate (UDC), a hydrophilic bile salt, could reduce mitochondrial liver injury from chronic ethanol consumption in rats. Animals were pair-fed liquid diets containing 36% of calories as ethanol or isocaloric carbohydrates. They were randomly assigned into 4 groups of 7 rats each and received a… CONTINUE READING