Uroporphyrin- and coproporphyrin I-accumulating mutant of Escherichia coli K12.


A new type of haem-deficient mutant was isolated in Escherichia coli K12 by neomycin selection. The mutant was deficient in uroporphyrinogen III cosynthase activity as indicated by the accumulation of uroporphyrin I and coproporphyrin. The mapping of the corresponding hemD gene by P1-mediated transduction showed that the new gene was located between ilv and cya, at min 83 on the chromosomal map of Escherichia coli K12.


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@article{Chartrand1979UroporphyrinAC, title={Uroporphyrin- and coproporphyrin I-accumulating mutant of Escherichia coli K12.}, author={Pierre Chartrand and Didier Tardif and A. Sasarman}, journal={Journal of general microbiology}, year={1979}, volume={110 1}, pages={61-6} }