Urodynamic effects of oxybutynin and tolterodine in conscious and anesthetized rats under different cystometrographic conditions

@article{Angelico2005UrodynamicEO,
  title={Urodynamic effects of oxybutynin and tolterodine in conscious and anesthetized rats under different cystometrographic conditions},
  author={Patrizia Angelico and Cristina Velasco and Luciano Guarneri and Giorgio Sironi and Amedeo Leonardi and Rodolfo Testa},
  journal={BMC Pharmacology},
  year={2005},
  volume={5},
  pages={14 - 14}
}
BACKGROUND Antimuscarinic agents are the most popular treatment for overactive bladder and their efficacy in man is well documented, producing decreased urinary frequency and an increase in bladder capacity. During cystometry in rats, however, the main effect reported after acute treatment with antimuscarinics is a decrease in peak micturition pressure together with little or no effect on bladder capacity. In the present experiments we studied the effects, in rats, of the two most widely used… CONTINUE READING

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Urodynamic effects of oral oxybutynin in conscious rats under different cystometrographic conditions

  • R Testa, P Angelico, C Velasco, L Guarneri, A Leonardi
  • 33rd International Continence Society Annual…
  • 2003
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