Urocortin in the lateral septal area modulates feeding induced by orexin A in the lateral hypothalamus.

@article{Wang2002UrocortinIT,
  title={Urocortin in the lateral septal area modulates feeding induced by orexin A in the lateral hypothalamus.},
  author={Chuanfeng Wang and Catherine M. Kotz},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2002},
  volume={283 2},
  pages={R358-67}
}
The intermediate portion of the lateral septum (LSi) contains high levels of urocortin (UCN) peptide and type 2 corticotropin-releasing hormone (CRH) receptor (CRHR2) and has anatomic and functional connections with the lateral hypothalamus (LH). We tested the effect of UCN in the LSi on feeding. Injection of 10 or 30 pmol UCN into LSi significantly decreased feeding in food-deprived rats for 24 h without producing conditioned taste aversion (CTA). Pretreatment with a CRH receptor antagonist… CONTINUE READING

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