Urocortin does not reduce the renal injury and dysfunction caused by experimental ischaemia/reperfusion.

@article{Patel2004UrocortinDN,
  title={Urocortin does not reduce the renal injury and dysfunction caused by experimental ischaemia/reperfusion.},
  author={Nimesh S. A. Patel and Marika Collin and Christoph Thiemermann},
  journal={European journal of pharmacology},
  year={2004},
  volume={496 1-3},
  pages={
          175-80
        }
}
Recent evidence indicates that activators of the serine/threonine kinase pathway protect against ischaemia/reperfusion. Here, we investigate the effects of renal ischaemia/reperfusion on the degree of renal dysfunction and injury with urocortin in rats. Rats treated with urocortin or its vehicle (saline) were subjected to bilateral renal artery occlusion (45 min) and reperfusion (6 h). At the end of experiments, the following indicators and markers of renal injury and dysfunction were measured… CONTINUE READING