Urocortin and the brain.

  title={Urocortin and the brain.},
  author={Weihong Pan and Abba J. Kastin},
  journal={Progress in neurobiology},
  volume={84 2},
Urocortin is a member of the corticotropin-releasing hormone (CRH) family of peptides. In the brain, its potent suppression of food intake is mediated by CRH receptors (CRHR). Urocortin also participates in the regulation of anxiety, learning, memory, and body temperature, and it shows neuroprotection. This review will summarize the location of urocortin-producing neurons and their projections, the pharmacological evidence of its actions in the CNS, and information acquired from knockout mice… CONTINUE READING
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