Corpus ID: 22793752

Urochordate betagamma-crystallin and the evolutionary origin of the vertebrate eye lens.

@article{Shimeld2005UrochordateBA,
  title={Urochordate betagamma-crystallin and the evolutionary origin of the vertebrate eye lens.},
  author={S. Shimeld and A. Purkiss and R. Dirks and O. Bateman and C. Slingsby and N. Lubsen},
  journal={Current biology : CB},
  year={2005},
  volume={15 18},
  pages={
          1684-9
        }
}
A refracting lens is a key component of our image-forming camera eye; however, its evolutionary origin is unknown because precursor structures appear absent in nonvertebrates. The vertebrate betagamma-crystallin genes encode abundant structural proteins critical for the function of the lens. We show that the urochordate Ciona intestinalis, which split from the vertebrate lineage before the evolution of the lens, has a single gene coding for a single domain monomeric betagamma-crystallin. The… Expand
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