Urochordate βγ-Crystallin and the Evolutionary Origin of the Vertebrate Eye Lens

@article{Shimeld2005UrochordateA,
  title={Urochordate $\beta$$\gamma$-Crystallin and the Evolutionary Origin of the Vertebrate Eye Lens},
  author={S. Shimeld and A. Purkiss and R. Dirks and O. Bateman and C. Slingsby and N. Lubsen},
  journal={Current Biology},
  year={2005},
  volume={15},
  pages={1684-1689}
}
A refracting lens is a key component of our image-forming camera eye; however, its evolutionary origin is unknown because precursor structures appear absent in nonvertebrates [1]. The vertebrate βγ-crystallin genes encode abundant structural proteins critical for the function of the lens [2]. We show that the urochordate Ciona intestinalis, which split from the vertebrate lineage before the evolution of the lens, has a single gene coding for a single domain monomeric βγ-crystallin. The crystal… Expand

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