Urine testing to monitor adherence to TB preventive therapy.

@article{Perry2002UrineTT,
  title={Urine testing to monitor adherence to TB preventive therapy.},
  author={Sharon Lee Perry and Melbourne F. Hovell and Elaine J. Blumberg and Jill P Berg and A Yakupova Vera and Carol Louise Sipan and Norma J. Kelley and Kathleen S. Moser and Antonino Catanzaro and Larry S. Friedman},
  journal={Journal of clinical epidemiology},
  year={2002},
  volume={55 3},
  pages={
          235-8
        }
}
This study examined the validity of the Arkansas urine test. One hundred ninety-four adolescents submitted an unannounced urine specimen monthly (for 6 to 8 months). Duplicate specimens were blindly tested with high agreement (kappa >90%). Sensitivity and specificity were estimated. In 68% of test runs, adolescents recalled taking INH within 24 hr of specimen collection. For recall intervals of 24, 48, and 72 hr, sensitivity was 87, 85, and 83%, respectively. Females were less likely to test… CONTINUE READING
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