Urine cytokines suggest an inflammatory response in the overactive bladder: a pilot study

  title={Urine cytokines suggest an inflammatory response in the overactive bladder: a pilot study},
  author={Pradeep Tyagi and Derek Barclay and Ruben Zamora and Naoki Yoshimura and Kenneth Peters and Yoram Vodovotz and Michael B Chancellor},
  journal={International Urology and Nephrology},
To study the hypothesis of detecting bladder inflammation associated with overactive bladder (OAB) through altered urine levels of cytokines, chemokines, and growth factors. Midstream urine specimens were collected from a prospective study done on eight asymptomatic control subjects and 17 idiopathic OAB patients. The urine was analyzed by a multiplex panel screen for 12 chemokines, cytokines, growth factors, and soluble receptors using Luminex™ xMAP® technology. Protein concentration values… CONTINUE READING


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