Urine as a Biological Specimen for Forensic Analysis of Alcohol and Variability in the Urine-to-Blood Relationship
@article{Jones2006UrineAA, title={Urine as a Biological Specimen for Forensic Analysis of Alcohol and Variability in the Urine-to-Blood Relationship}, author={Alan Wayne Jones}, journal={Toxicological Reviews}, year={2006}, volume={25}, pages={15-35} }
This article concerns the use of urine as a biological specimen for determination of alcohol in clinical and forensic toxicology and discusses factors that might influence variability in the urine/blood concentration ratio of alcohol. A large number of human drinking experiments were conducted to determine the time course of urine-alcohol concentrations (UAC) in relation to blood-alcohol concentrations (BAC). The UAC and BAC curves were shifted in time and the BAC curve always began to decrease…
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References
SHOWING 1-10 OF 118 REFERENCES
An automated alcohol dehydrogenase method for ethanol quantification in urine and whole blood.
- MedicineJournal of analytical toxicology
- 2005
The method robustness to routine analysis of urine and blood specimens during a period of eight months is shown and the method was compared with two headspace gas chromatography-flame ionization detection methods using authentic forensic urine specimens.
Measuring Alcohol in Blood and Breath for Forensic Purposes - A Historical Review.
- Medicine
- 1996
The technology of breath-alcohol testing has changed dramatically over the years from chemical oxidation and colorimetric procedures towards physicochemical techniques such as gas chromatography, electrochemical oxidation, and multiple wavelength infrared spectrophotometry.
The Relationship between Blood and Urine Alcohol Concentrations at Autopsy
- MedicineMedicine, science, and the law
- 1989
It was concluded that the main value in determining the urine alcohol concentration at autopsy was to exclude the possibility of the alcohol present in the blood sample having been generated during the post-mortem interval.
Reference limits for urine/blood ratios of ethanol in two successive voids from drinking drivers.
- MedicineJournal of analytical toxicology
- 2002
These reference limits are appropriate to use when a person's venous BAC needs to be estimated with reasonable scientific certainty from the concentration determined in specimens of urine.
THE COMPARATIVE CONCENTRATIONS OF ALCOHOL IN HUMAN BLOOD AND URINE AT INTERVALS AFTER INGESTION
- Medicine
- 1922
Both blood and urine reach their maximum alcohol concentration at about the same time and while not identical still the urine-alcohol curve is very useful for comparison with the time relations of the objective measurements of the alcohol effect on the central nervous system.
Urine/blood ratios of ethanol in deaths attributed to acute alcohol poisoning and chronic alcoholism.
- MedicineForensic science international
- 2003
Monitoring ethanol exposure in a clinical setting by analysis of blood, breath, saliva, and urine.
- MedicineAlcoholism, clinical and experimental research
- 1999
BACKGROUND
Several new technologies have been developed for estimating blood alcohol concentration (BAC), among others, by the analysis of alcohol in saliva specimens. The Q.E.D. is a new…
Ethanol distribution ratios between urine and capillary blood in controlled experiments and in apprehended drinking drivers.
- MedicineJournal of forensic sciences
- 1992
The status of alcohol absorption needs to be documented if drinking drivers claim ingestion of alcohol after the offence or when back-estimation of the BAC from the time of sampling to the timeof driving is required by statute.
Lack of association between urinary creatinine and ethanol concentrations and urine/blood ratio of ethanol in two successive voids from drinking drivers.
- MedicineJournal of analytical toxicology
- 1998
It is demonstrated that the relative dilution of urine specimens, as reflected in creatinine content, is not associated with the concentration of ethanol in the urine samples or with the UAC/BAC ratio.
CONCENTRATIONS OF ALCOHOL IN SAMPLES OF BLOOD AND URINE TAKEN AT THE SAME TIME.
- MedicineJournal - Forensic Science Society
- 1965