Urine Toxicology Screening Among Chronic Pain Patients on Opioid Therapy: Frequency and Predictability of Abnormal Findings

@article{Michna2007UrineTS,
  title={Urine Toxicology Screening Among Chronic Pain Patients on Opioid Therapy: Frequency and Predictability of Abnormal Findings},
  author={Edward Michna and Robert N. Jamison and L. Pham and Edgar L Ross and David R. Janfaza and Srdjan S. Nedeljkovic and Sanjeet Narang and Diane Palombi and Ajay D. Wasan},
  journal={The Clinical Journal of Pain},
  year={2007},
  volume={23},
  pages={173-179}
}
ObjectiveTo examine the incidence of abnormal urine toxicology screening among chronic pain patients prescribed opioids for their pain and to relate these results to patient descriptors and type, number, and dose of prescribed opioids. MethodsA retrospective analysis of data from 470 patients who had urine screening at a pain management program in an urban teaching hospital was performed. Urine samples were analyzed using gas chromatography-mass spectrometry. Patients were categorized as having… 
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188 Citations
Highly Influential Citations
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Methods Citations
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Identifying Prevalence of and Risk Factors for Abnormal Urine Drug Tests in Cancer Pain Patients.
The role of urine toxicology in chronic opioid analgesic therapy.
  • P. Compton
  • Medicine
    Pain management nursing : official journal of the American Society of Pain Management Nurses
  • 2007
Retrospective review of physician opioid prescribing practices in patients with aberrant behaviors.
TLDR
Results of the study showed that the patients exhibiting aberrant drug behaviors have similar pain and psychiatric diagnoses as other chronic pain patients and the role of the urine drug screen in influencing prescriber behaviors is discussed.
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TLDR
The study found motivations for urine testing and testing practices varied widely, and urine testing, despite its clinical utility, is not used consistently.
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TLDR
Repeated UDT testing should be used as an important adjunctive tool to help guide clinical decision-making regarding opioid therapy, potentially increasing future quality of care and improving overall pain management.
Urine and oral fluid drug testing in support of pain management
TLDR
This review discusses the issues that most affect the clinical utility of drug testing in chronic pain management with opioid therapy, and focuses on the two most commonly used specimen matrices in drug testing: urine and oral fluid.
Illicit drug use correlates with negative urine drug test results for prescribed hydrocodone, oxycodone, and morphine.
TLDR
The hypothesis that people who are positive for their prescribed medications use fewer illicit drugs than those who do not take their medications is supported, and it may be beneficial for physicians to test more thoroughly for illicit drugs when patients' drug tests are negative for theircribed medications.
Interviewing and Urine Drug Toxicology Screening in a Pediatric Pain Management Center: An Analysis of Analgesic Nonadherence and Aberrant Behaviors in Adolescents and Young Adults
TLDR
UDT could be used in conjunction with careful clinical interviewing to substantiate patient report and increase the likelihood of detecting analgesic nonadherence and aberrant behaviors, as well as highlighting the challenges of identifyingNonadherence to a prescription regimen among adolescents with chronic pain.
The Role of Urine Drug Testing In Chronic Pain Management: 2013 Update
Of 470 patients treated in an urban pain management setting, 45% were found retrospectively to have inconsistent urine screens, defined as the absence of a prescribed opioid, the presence of illicit…
Do Urine Drug Tests Reveal Substance Misuse Among Patients Prescribed Opioids for Chronic Pain?
TLDR
Expert adjudication of UDT results identified clinical concern for substance misuse in 37% of patients receiving opioids for chronic pain, and patients aged 18–34 years were more likely to have concerning U DT results.
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