Urinary soluble urokinase receptor levels are elevated and pathogenic in patients with primary focal segmental glomerulosclerosis

@inproceedings{Huang2014UrinarySU,
  title={Urinary soluble urokinase receptor levels are elevated and pathogenic in patients with primary focal segmental glomerulosclerosis},
  author={Jing Huang and Gang Liu and Yi-miao Zhang and Zhao Jie Cui and Fang Wang and Xiaojing Liu and Rong Chu and Ming-Hui Zhao},
  booktitle={BMC medicine},
  year={2014}
}
BACKGROUND Focal segmental glomerulosclerosis (FSGS) is a major cause of end-stage renal disease. Recent studies have proposed that plasma soluble urokinase receptor (suPAR) might be a causative circulating factor but this proposal has caused controversy. This study aimed to measure urinary suPAR levels in patients with primary FSGS and its significance in the pathogenesis of FSGS. METHODS Sixty-two patients with primary FSGS, diagnosed between January 2006 and January 2012, with complete… CONTINUE READING
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References

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Association of histologic variants in FSGS clinical trial with presenting features and outcomes.

Clinical journal of the American Society of Nephrology : CJASN • 2013
View 1 Excerpt

Transmission of glomerular permeability factor soluble urokinase plasminogen activator receptor (suPAR) from a mother to child.

American journal of kidney diseases : the official journal of the National Kidney Foundation • 2013
View 1 Excerpt

Amiloride off-target effect inhibits podocyte urokinase receptor expression and reduces proteinuria.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association • 2012
View 1 Excerpt

Circulating suPAR in two cohorts of primary FSGS.

Journal of the American Society of Nephrology : JASN • 2012

Deegens JK: Serum-soluble urokinase receptor concentration in primary FSGS

RJ Maas, JF Wetzels
Kidney Int • 2012
View 3 Excerpts

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