Urinary serotonin metabolite excretion during cisplatin chemotherapy.

@article{WilderSmith1993UrinarySM,
  title={Urinary serotonin metabolite excretion during cisplatin chemotherapy.},
  author={Oliver H G Wilder-Smith and Alain Borgeat and Philippe Chappuis and Mohammad Fathi and Marco Forni},
  journal={Cancer},
  year={1993},
  volume={72 7},
  pages={2239-41}
}
BACKGROUND Nausea and vomiting associated with cisplatin chemotherapy is a source of major morbidity that remains difficult to control. Acute phase (0-24 hours after induction of chemotherapy) nausea and vomiting parallels plasma serotonin release, which explains the effectiveness of 5HT3 antagonists; serotonin release in the delayed phase (24-48 hours after induction), during which consistent antiemetic control remains elusive, has not been investigated. The effect of propofol, a recent… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 18 extracted citations

Prevention of nausea and vomiting associated with stem cell transplant: results of a prospective, randomized trial of aprepitant used with highly emetogenic preparative regimens.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation • 2013
View 1 Excerpt

Similar Papers

Loading similar papers…