Urinary screening tests for fetal Down syndrome: I. Fresh beta-core fragment.

@article{Cole1999UrinaryST,
  title={Urinary screening tests for fetal Down syndrome: I. Fresh beta-core fragment.},
  author={Laurence A. Cole and Kirsi Marja Rinne and Satish M. Mahajan and Utku A Oz and Shohreh Shahabi and Maurice J. Mahoney and Ray O. Bahado-Singh},
  journal={Prenatal diagnosis},
  year={1999},
  volume={19 4},
  pages={
          340-50
        }
}
Variable results have been reported using urine beta-core fragment as a marker for fetal Down syndrome. Initial studies by Cuckle et al. (1994) and Canick et al. (1995) indicated that beta-core fragment was an outstanding marker, detecting >80 per cent of Down syndrome cases. Since these reports, widely varying results have been published, indicating between 20 per cent and 66 per cent detection of cases at 5 per cent false-positive rate. The wide variation in the reported data has led to a… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-9 of 9 extracted citations