Urinary obstruction causes irreversible renal failure by inducing chronic tubulointerstitial nephritis.

@article{Coroneos1997UrinaryOC,
  title={Urinary obstruction causes irreversible renal failure by inducing chronic tubulointerstitial nephritis.},
  author={E J Coroneos and M Assouad and Bhuvaneswari Krishnan and Luan Truong},
  journal={Clinical nephrology},
  year={1997},
  volume={48 2},
  pages={125-8}
}
Obstruction of urinary tract is a frequent cause of transient renal dysfunction, which, in the majority of cases, is reversible. Urinary obstruction can occasionally cause chronic renal failure, in spite of successful relief of the obstruction. Sonographic and pathologic studies show renal atrophy, interstitial fibrosis, and interstitial inflammation, which explain the loss of renal function. Herein, we report two cases of bilateral obstructive nephropathy due to prostatic hyperplasia, in which… CONTINUE READING
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