Urinary neutrophil gelatinase-associated lipocalin (NGAL) is an early biomarker for renal tubulointerstitial injury in IgA nephropathy.

@article{Ding2007UrinaryNG,
  title={Urinary neutrophil gelatinase-associated lipocalin (NGAL) is an early biomarker for renal tubulointerstitial injury in IgA nephropathy.},
  author={Hanlu Ding and Ya-Ni He and Kailong Li and Jurong Yang and Xiaolin Li and Rong Lu and Wenda Gao},
  journal={Clinical immunology},
  year={2007},
  volume={123 2},
  pages={227-34}
}
Renal tubulointerstitial injury plays an important role in the development of IgA nephropathy (IgAN), the most common form of glomerulonephritis. Few currently in use biomarkers can sensitively detect the earliest signs of renal tubular injury, hindering our efforts to launch preventive and therapeutic measures for this disorder in a timely manner. Neutrophil gelatinase-associated lipocalin (NGAL) is an acute phase protein that is rapidly released from not only neutrophils but also a variety of… CONTINUE READING