Urinary metabolites of daidzin orally administered in rats.

  title={Urinary metabolites of daidzin orally administered in rats.},
  author={Takaaki Yasuda and Keisuke Ohsawa},
  journal={Biological & pharmaceutical bulletin},
  volume={21 9},
In a study on the metabolism of flavonoids, the isoflavone glycoside daidzin was orally administered to rats. Urine samples were collected and treated with beta-glucuronidase and arylsulfatase. Aglycone daidzein (M3) and other three metabolites, 3',4',7-trihydroxyisoflavone (M1), 4',7-dihydroxyisoflavanone (M2) and 4',7-dihydroxyisoflavan (M4) were isolated from the urine following treatment with enzymes. The structures of M1, M2 and M4 were determined on the basis of chemical and spectral data… CONTINUE READING

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