Urinary metabolic phenotyping differentiates children with autism from their unaffected siblings and age-matched controls.

@article{Yap2010UrinaryMP,
  title={Urinary metabolic phenotyping differentiates children with autism from their unaffected siblings and age-matched controls.},
  author={Ivan Kok Seng Yap and Manya Therese Angley and Kirill A. Veselkov and Elaine Holmes and John C. Lindon and Jeremy K. Nicholson},
  journal={Journal of proteome research},
  year={2010},
  volume={9 6},
  pages={
          2996-3004
        }
}
Autism is an early onset developmental disorder with a severe life-long impact on behavior and social functioning that has associated metabolic abnormalities. The urinary metabolic phenotypes of individuals (age range=3-9 years old) diagnosed with autism using the DSM-IV-TR criteria (n = 39; male = 35; female = 4), together with their nonautistic siblings (n = 28; male = 14; female = 14) and age-matched healthy volunteers (n = 34, male = 17; female = 17) have been characterized for the first… CONTINUE READING
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