Urinary leukotriene E4 and 11-dehydro-thromboxane B2 excretion in children with bronchial asthma


Background: Cysteinyl leukotrienes (CysLTs) and thromboxane (TX) A 2 have been implicated in the pathogenesis of bronchial asthma. Urinary leukotriene E 4 (LTE 4 ) and 11-dehydro-TXB 2 (11DTXB 2 ) levels are often used to assess the production of CysLTs and TXA 2 . However, few studies have examined the products of these two mediators in the same asthmatic… (More)


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