Urinary high molecular weight matrix metalloproteinases as non-invasive biomarker for detection of bladder cancer

@inproceedings{Mohammed2013UrinaryHM,
  title={Urinary high molecular weight matrix metalloproteinases as non-invasive biomarker for detection of bladder cancer},
  author={Mohammed Amin Mohammed and Manar F Seleim and Mohga Shafik Abdalla and Hayat Mohamed Sharada and Abdel Hady Abdel Wahab},
  booktitle={BMC urology},
  year={2013}
}
BACKGROUND Matrix Metalloproteinases (MMPs) are key molecules for tumor growth, invasion and metastasis. Over-expression of different MMPs in tumor tissues can disturb the homeostasis and increase the level of various body fluids. Many MMPs including high molecular weights (HMWs) were detected in the urine of prostate and bladder cancer patients. Our aim here is to assess the usefulness of HMW MMPs as non invasive biomarkers in bilharzial bladder cancer in Egyptian patients. METHODS The… CONTINUE READING

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