Urinary haptoglobin, alpha-1 anti-chymotrypsin and retinol binding protein identified by proteomics as potential biomarkers for lupus nephritis.

@article{Aggarwal2017UrinaryHA,
  title={Urinary haptoglobin, alpha-1 anti-chymotrypsin and retinol binding protein identified by proteomics as potential biomarkers for lupus nephritis.},
  author={Amita Aggarwal and Rakesh Kumar Gupta and Vir Singh Negi and Liza Rajasekhar and Ramnath Misra and Pratibha Singh and Vinita Chaturvedi and Sumit Sinha},
  journal={Clinical and experimental immunology},
  year={2017},
  volume={188 2},
  pages={
          254-262
        }
}
The study was aimed at identification by proteomics and validation by enzyme-linked immunosorbent assay (ELISA) of potential urinary biomarkers for lupus nephritis. Study subjects comprised 88 systemic lupus erythematosus (SLE) patients and 60 controls (rheumatoid arthritis, diabetes mellitus and healthy individuals). Based on the SLE disease activity index (SLEDAI), patients were classified as active renal (AR), active non-renal (ANR) or inactive disease (ID). Urinary proteins from a group of… CONTINUE READING
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