Urinary glycosaminoglycan composition in chronic glomerulonephritis.

  title={Urinary glycosaminoglycan composition in chronic glomerulonephritis.},
  author={Pierina De Muro and Rossana Faedda and Andrea Ercole Satta and Donatella Finetti and Antonio Giovanni Emilio Masala and Alessandro Cigni and Giovanni Maria Sanna and Gian Mario Cherchi},
  journal={Journal of nephrology},
  volume={18 2},
BACKGROUND Glycosaminoglycans (GAG) play an important role in regulating glomerular permeability, and a reduction in their plasmatic concentration or urinary loss has been implicated in the pathogenesis of diseases associated with increased albumin permeability. The purpose of this study was to evaluate GAG excretion in renal pathology by analyzing the composition of urinary GAG in antibody mediated glomerular injury, such as mesangial glomerulonephritis (IgAGN) and primitive membranous… CONTINUE READING

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