Urinary excretion of free and acetylated polyamines in hepatocellular carcinoma.

@article{Antoniello1998UrinaryEO,
  title={Urinary excretion of free and acetylated polyamines in hepatocellular carcinoma.},
  author={S. Antoniello and M. Auletta and Paolo Magri and Fernando Pardo},
  journal={The International journal of biological markers},
  year={1998},
  volume={13 2},
  pages={
          92-7
        }
}
Polyamines (putrescine, spermidine and spermine) are essential for the proliferation of normal and neoplastic cells, and have been repeatedly recommended as tumor markers, with contrasting and elusive results. In the present study the urinary excretion of free and acetylated polyamines was measured in patients with hepatocellular carcinoma (HCC), cirrhotics and control subjects. Separation and quantification of dansyl-derivatives of free, acetylated and total polyamines was performed by reverse… CONTINUE READING