Urinary excretion of biopterin and neopterin in psychiatric disorders.

  title={Urinary excretion of biopterin and neopterin in psychiatric disorders.},
  author={David S. Duch and Jeffrey H. Woolf and Charles A. Nichol and Jonathan R. T. Davidson and James C. Garbutt},
  journal={Psychiatry research},
  volume={11 2},
Levels of urinary neopterin and biopterin were determined in patients having a diagnosis of schizophrenia, unipolar depression, or bipolar depression. Both neopterin and biopterin levels were significantly higher in the urine of patients with unipolar depression than in the urine of the control group. Subclassification of patients into primary and secondary depression demonstrated a significant elevation of urinary biopterin in both groups, whereas urinary neopterin was elevated only in those… CONTINUE READING