Urinary excretion of arsenic metabolites after long-term oral administration of various arsenic compounds to rats.

@article{Yoshida1998UrinaryEO,
  title={Urinary excretion of arsenic metabolites after long-term oral administration of various arsenic compounds to rats.},
  author={Ken-ichi Yoshida and Yuji Inoue and Koichi Kuroda and H Chen and Hideki Wanibuchi and Shoji Fukushima and Ginji Endo},
  journal={Journal of toxicology and environmental health. Part A},
  year={1998},
  volume={54 3},
  pages={179-92}
}
The metabolism of arsenic compounds in rats was studied by comparing urinary metabolites of arsenic compounds administered for 1 wk or 7 mo. Male F344/DuCrj rats were given 100 mg As/L as monomethylarsonic acid (MMA), dimethylarsinic acid (DMA), trimethylarsine oxide (TMAO), or arsenobetaine (AsBe), or 10 mg As/L as arsenite [As(III)] via drinking water for 7 mo. Urine was collected by forced urination after 1 wk or 7 mo. Arsenic metabolites in urine were analyzed by ion chromatography with… CONTINUE READING