Urinary excretion of aquaporin-2 in humans: a potential marker of collecting duct responsiveness to vasopressin.

@article{Elliot1996UrinaryEO,
  title={Urinary excretion of aquaporin-2 in humans: a potential marker of collecting duct responsiveness to vasopressin.},
  author={Sheila Elliot and Paul Goldsmith and Mark A. Knepper and Marianne Haughey and Beth H Olson},
  journal={Journal of the American Society of Nephrology : JASN},
  year={1996},
  volume={7 3},
  pages={403-9}
}
The vasopressin-sensitive water channel (aquaporin 2; AQP-2) mediates water transport across the apical plasma membrane of the renal collecting ducts and is excreted in human urine. This study presents the hypothesis that measurements of the AQP-2 excretion rate might be used as a marker of collecting-duct responsiveness to vasopressin, and therefore could be useful in the clinical evaluation of various water-balance disorders. This study presents information about the development of an… CONTINUE READING

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