Urinary cystatin C as an early biomarker of acute kidney injury after open and endovascular abdominal aortic aneurysm repair.

@article{Pirgakis2014UrinaryCC,
  title={Urinary cystatin C as an early biomarker of acute kidney injury after open and endovascular abdominal aortic aneurysm repair.},
  author={Konstantinos M Pirgakis and Konstantinos Makris and Ilias Dalainas and Andreas M. Lazaris and Chrisostomos K Maltezos and Christos D. Liapis},
  journal={Annals of vascular surgery},
  year={2014},
  volume={28 7},
  pages={1649-58}
}
BACKGROUND Acute kidney injury (AKI) after open repair (OR) and endovascular repair (EVAR) of abdominal aortic aneurysm (AAA) is associated with increased mortality and hospital costs. Early detection of AKI is critical to prevent its progression. Recent findings demonstrate that elevated levels of urinary cystatin C (uCysC) may reflect tubular dysfunction. We prospectively evaluated whether uCysC can detect renal dysfunction earlier than serum creatinine (sCr). METHODS In a prospective study… CONTINUE READING

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