Urinary and serum biomarkers for the diagnosis of acute kidney injury: an in-depth review of the literature.

@article{Vanmassenhove2013UrinaryAS,
  title={Urinary and serum biomarkers for the diagnosis of acute kidney injury: an in-depth review of the literature.},
  author={Jill Vanmassenhove and Raymond Camille Vanholder and Evi Vanessa Nagler and Wim Van Biesen},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={2013},
  volume={28 2},
  pages={254-73}
}
BACKGROUND Acute kidney injury (AKI) remains associated with high morbidity and mortality, despite progress in medical care. Although the RIFLE (Risk, Injury, Failure, Loss, End-Stage Kidney Disease) and AKIN (Acute Kidney Injury Network) criteria, based on serum creatinine and urine output, were a step forward in diagnosing AKI, a reliable tool to differentiate between true parenchymal and pre-renal azotaemia in clinical practice is still lacking. In the last decade, many papers on the use of… CONTINUE READING
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