Urinary Proteomic Biomarkers for Diagnosis and Risk Stratification of Autosomal Dominant Polycystic Kidney Disease: A Multicentric Study

@inproceedings{Kistler2013UrinaryPB,
  title={Urinary Proteomic Biomarkers for Diagnosis and Risk Stratification of Autosomal Dominant Polycystic Kidney Disease: A Multicentric Study},
  author={Andreas D Kistler and Andreas L Serra and Justyna Siwy and Diane Poster and Fabienne Krauer and Vicente E. Torres and Michal M Mrug and J. J. Grantham and K. T. Bae and James E. Bost and William Mullen and Rudolf Peter W{\"u}thrich and Harald Mischak and Arlene B. Chapman},
  booktitle={PloS one},
  year={2013}
}
Treatment options for autosomal dominant polycystic kidney disease (ADPKD) will likely become available in the near future, hence reliable diagnostic and prognostic biomarkers for the disease are strongly needed. Here, we aimed to define urinary proteomic patterns in ADPKD patients, which aid diagnosis and risk stratification. By capillary electrophoresis online coupled to mass spectrometry (CE-MS), we compared the urinary peptidome of 41 ADPKD patients to 189 healthy controls and identified… CONTINUE READING

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