Urinary NAG in children with urolithiasis, nephrocalcinosis, or risk of urolithiasis

  title={Urinary NAG in children with urolithiasis, nephrocalcinosis, or risk of urolithiasis},
  author={Przemyslaw Sikora and Sara Glatz and Bodo Bernhard Beck and Ludwig Stapenhorst and Malgorzata Zajaczkowska and Albrecht Hesse and Bernd Hoppe},
  journal={Pediatric Nephrology},
A crucial role for cell-crystal interactions in the development of urolithiasis (UL) and nephrocalcinosis (NC) was previously observed in experiments with different cell lines mimicking renal epithelial cells. It was found that such cell-crystal interactions lead to tubular damage and/or or dysfunction. To find further proof for these observations, we measured the urinary N-acetyl-β-d-glucosaminidase (NAG) excretion, a marker of proximal tubular damage, in children with UL or NC and in children… CONTINUE READING
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  • RL Hackett, PN Shevock, Khan
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