Urinary Loss of Tricarboxylic Acid Cycle Intermediates As Revealed by Metabolomics Studies: An Underlying Mechanism to Reduce Lipid Accretion by Whey Protein Ingestion?

@inproceedings{Lillefosse2014UrinaryLO,
  title={Urinary Loss of Tricarboxylic
Acid Cycle Intermediates
As Revealed by Metabolomics Studies: An Underlying Mechanism to Reduce
Lipid Accretion by Whey Protein Ingestion?},
  author={Haldis Hauk{\aa}s Lillefosse and Morten Rahr Clausen and Christian Clement Yde and Ditte Bruun Ditlev and Xumin Zhang and Zhen-Yu Du and Hanne Christine Bertram and Lise Madsen and Karsten Kristiansen and Bj\orn Liaset},
  booktitle={Journal of proteome research},
  year={2014}
}
Whey protein intake is associated with the modulation of energy metabolism and altered body composition both in human subjects and in animals, but the underlying mechanisms are not yet elucidated. We fed obesity-prone C57BL/6J mice high-fat diets with either casein (HF casein) or whey (HF whey) for 6 weeks. At equal energy intake and apparent fat and nitrogen digestibility, mice fed HF whey stored less energy as lipids, evident both as lower white adipose tissue mass and as reduced liver lipids… CONTINUE READING
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Proteomic and Functional Analysis of Liver Mitochondria from High Fat Diet Diabetic Mice

E. Fabbrini, S. Sullivan, S. Klein
Mol. Cell. Proteomics • 2013

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