Urinary Interleukin-8 Is a Biomarker of Stress in Emergency Physicians, Especially with Advancing Age — The JOBSTRESS* Randomized Trial

@inproceedings{Dutheil2013UrinaryII,
  title={Urinary Interleukin-8 Is a Biomarker of Stress in Emergency Physicians, Especially with Advancing Age — The JOBSTRESS* Randomized Trial},
  author={Fr{\'e}d{\'e}ric Dutheil and Marion Trousselard and Christophe Perrier and G{\'e}rard Lac and Alain Chamoux and Martine Duclos and Geraldine Naughton and George Mnatzaganian and Jeannot Schmidt},
  booktitle={PloS one},
  year={2013}
}
BACKGROUND Emergency physicians are exposed to greater stress during a 24-hour shift (24 hS) than a 14-hour night shift (14 hS), with an impact lasting several days. Interleukin-8 (IL-8) is postulated to be a chronic stress biomarker. However, no studies have tracked IL-8 over several shifts or used it for monitoring short-term residual stress. The IL-8 response to the shifts may also increase with age. Conveniently, IL-8 can be measured non-intrusively from urine. METHODS We conducted a… CONTINUE READING
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