Urinary Exosomes: A Novel Means to Non-Invasively Assess Changes in Renal Gene and Protein Expression

Abstract

BACKGROUND In clinical practice, there is a lack of markers for the non-invasive diagnosis and follow-up of kidney disease. Exosomes are membrane vesicles, which are secreted from their cells of origin into surrounding body fluids and contain proteins and mRNA which are protected from digestive enzymes by a cell membrane. METHODS Toxic podocyte damage was… (More)
DOI: 10.1371/journal.pone.0109631

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