Urinary Concentrations of Triclosan in the U.S. Population: 2003–2004

  title={Urinary Concentrations of Triclosan in the U.S. Population: 2003–2004},
  author={Antonia M. Calafat and Xiaoyun Ye and L Y Wong and John A. Reidy and Larry L. Needham},
  journal={Environmental Health Perspectives},
  pages={303 - 307}
Background Triclosan is a synthetic chemical with broad antimicrobial activity that has been used extensively in consumer products, including personal care products, textiles, and plastic kitchenware. Objectives This study was designed to assess exposure to triclosan in a representative sample ≥ 6 years of age of the U.S. general population from the 2003–2004 National Health and Nutrition Examination Survey (NHANES). Methods We analyzed 2,517 urine samples using automated solid-phase extraction… 

Figures and Tables from this paper

Urinary Concentrations of Four Parabens in the U.S. Population: NHANES 2005–2006

Differences in the urinary concentrations of MP and PP by sex and race/ethnicity likely reflect the use of personal care products containing these compounds.

Triclosan in individual human milk samples from Australia.

Urinary Concentrations of the Antibacterial Agent Triclocarban in United States Residents: 2013-2014 National Health and Nutrition Examination Survey.

This first nationally representative assessment of exposure to triclocarban among Americans ≥6 years of age who participated in the 2013-2014 National Health and Nutrition Examination Survey finds no correlations between urinary concentrations of tricLocarban and triclosan.

Exposure to Free and Conjugated Forms of Bisphenol A and Triclosan among Pregnant Women in the MIREC Cohort

The results from this study represent the largest national-level data on urinary concentrations of free and conjugated forms of BPA and TCS in pregnant women and suggest that maternal characteristics predicting elevated urine concentrations of these phenols largely act in opposite directions.

Chinese population exposure to triclosan and triclocarban as measured via human urine and nails

Nail samples can be applied to the biomonitoring for TCS and TCC in the general population, and the levels of both chemicals were higher in females than in males for urine and fingernail samples, but no significant differences were found between different genders for either compound in toenails.

Environmental Exposure to Triclosan and Semen Quality

The findings suggest that the adverse effect of TCS on semen quality is modest at the environment-relevant dose in humans, and further studies are needed to confirm the findings.

Analysis of triclosan and triclocarban in human nails using isotopic dilution liquid chromatography-tandem mass spectrometry.




Pharmacokinetics of Triclosan Following Oral Ingestion in Humans

Triclosan appears to be readily absorbed from the gastrointestinal tract and has a rapid turnover in humans, and the high lipid solubility of the substance gives rise to questions regarding distribution properties and accumulation.

Co-occurrence of triclocarban and triclosan in U.S. water resources.

Quantitative structure-activity relationship (QSAR) analyses suggest that TCC is a previously unrecognized contaminant of U.S. water resources nationwide, likely ranking in the top 10 in occurrence rate and the top 20 in maximum concentration among 96 organic pollutants considered.

Urinary Creatinine Concentrations in the U.S. Population: Implications for Urinary Biologic Monitoring Measurements

The normal range of urinary creatinine concentrations among various demographic groups are documented, the impact that variations in creatinin concentrations can have on classifying exposure status of individuals in epidemiologic studies are evaluated, and an approach using multiple regression to adjust for variations in Creatinine in multivariate analyses is recommended.

Temporal variability of urinary levels of nonpersistent insecticides in adult men

Although a single sample adequately predicted longer-term average exposure, a second sample collected at least 1 month following the first sample would reduce exposure measurement error.

Pilot Study of Urinary Biomarkers of Phytoestrogens, Phthalates, and Phenols in Girls

A wide spectrum of hormonally active exposure biomarkers were detectable and variable among young girls, with high maximal concentrations > 1,000 μg/L found for several analytes and varied by characteristics that may be relevant to development.

Triclosan: applications and safety.

Triclosan and antimicrobial resistance in bacteria: an overview.

Wide use of triclosan may represent a potential public health risk in regard to development of concomitant resistance to clinically important antimicrobials, as confirmed in Escherichia coli and Salmonella enterica.