Urinary Angiotensinogen Level Predicts AKI in Acute Decompensated Heart Failure: A Prospective, Two-Stage Study.

@article{Yang2015UrinaryAL,
  title={Urinary Angiotensinogen Level Predicts AKI in Acute Decompensated Heart Failure: A Prospective, Two-Stage Study.},
  author={Xiaobing Yang and Chunbo Chen and Jianwei Tian and Yan Zha and Yuqin Xiong and Zhaolin Sun and Pingyan Chen and Jun Li and Tiecheng Yang and Changsheng Ma and Hua-Feng Liu and Xiaobin Wang and Fan-fan Hou},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2015},
  volume={26 8},
  pages={2032-41}
}
A major challenge in prevention and early treatment of acute cardiorenal syndrome (CRS) is the lack of high-performance predictors. To test the hypothesis that urinary angiotensinogen (uAGT) is an early predictor for acute CRS and 1-year prognosis in patients with acute decompensated heart failure (ADHF), we performed a prospective, two-stage, multicenter cohort study in patients with ADHF. In stage I (test set), 317 patients were recruited from four centers. In stage II (validation set), 119… CONTINUE READING
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