Urinary Angiotensin Converting Enzyme 2 Increases in Patients With Type 2 Diabetic Mellitus

@article{Liang2015UrinaryAC,
  title={Urinary Angiotensin Converting Enzyme 2 Increases in Patients With Type 2 Diabetic Mellitus},
  author={Yaoxian Liang and H. Deng and S. Bi and Zhuan Cui and A L. and Danxia Zheng and Yue Wang},
  journal={Kidney and Blood Pressure Research},
  year={2015},
  volume={40},
  pages={101 - 110}
}
Background/Aims: Angiotensin converting enzyme 2 (ACE2) is highly expressed in the kidney and recognized to be renoprotective by degrading Angiotensin II to Angiotensin (1-7) in diabetic nephropathy. However, little is known about the role of urinary ACE2 (UACE2) in diabetes. The present study was performed to evaluate UACE2 levels in type 2 diabetic patients with various degrees of albuminuria and its associations with metabolic parameters. The effect of RAS inhibitors on UACE2 excretion was… Expand
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