Uridine enhances the cytotoxic effect of D-glucosamine in rat C6 glioma cells.

@article{Calvaruso1986UridineET,
  title={Uridine enhances the cytotoxic effect of D-glucosamine in rat C6 glioma cells.},
  author={Giuseppe Calvaruso and Gennaro Taibi and Maria Valeria Torregrossa and Nino Romano and Giovanni Tesoriere},
  journal={Life sciences},
  year={1986},
  volume={39 23},
  pages={
          2221-7
        }
}
This paper studies the influence of uridine on the effects exerted by D-glucosamine in rat C6 glioma cells. 2 mM uridine increased markedly both the cytotoxic effect of the aminosugar and the inhibition of thymidine incorporation into acid-insoluble fraction. Furthermore the complete resumption of the capacity to incorporate either 3H-thymidine or 3H-mannose which was observed after the removal of the aminosugar, was impeded when the cells were treated contemporaneously with D-glucosamine and… Expand
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