Uridine binding by Zn(II) macrocyclic complexes: diversion of RNA cleavage catalysts.

@article{Rossiter2005UridineBB,
  title={Uridine binding by Zn(II) macrocyclic complexes: diversion of RNA cleavage catalysts.},
  author={Clifford S Rossiter and Ryan A Mathews and Janet R Morrow},
  journal={Inorganic chemistry},
  year={2005},
  volume={44 25},
  pages={9397-404}
}
Zn(II) complexes of 1-oxa-4,7,10-triazacyclododecane (12[ane]N3O), 1,5,9-triazacyclododecane (12[ane]N3), and 1-hydroxyethyl-1,4,7-triazacyclononane (9[ane]N3OH) promote cleavage of the RNA analogue, 2-hydroxypropyl-4-nitrophenyl phosphate (HpPNP) at pH 8.0, I=0.10 M (NaCl), 25 degrees C with second-order rate constants of 8.9x10(-3), 9.0x10(-3), and 3.3x10… CONTINUE READING