Urethral development in the fetal rabbit and induction of hypospadias: a model for human development.

@article{Kurzrock2000UrethralDI,
  title={Urethral development in the fetal rabbit and induction of hypospadias: a model for human development.},
  author={Eric Kurzrock and Priya Jegatheesan and Gerald R. Cunha and Laurence S. Baskin},
  journal={The Journal of urology},
  year={2000},
  volume={164 5},
  pages={1786-92}
}
PURPOSE To determine whether the development of the rabbit phallus would be an appropriate model of human phallic development, we evaluated the formation of the fetal rabbit phallus and attempted to induce hypospadias pharmacologically. MATERIALS AND METHODS New Zealand rabbit fetuses were obtained on gestational days 20 to 24, 26, 28 and 31. Sex was determined by gonadal morphology, and 6 fetuses were obtained at each age. The perineum was dissected, fixed, sectioned and stained with… CONTINUE READING
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