Ureteropelvic junction obstruction: morphological and clinical studies

  title={Ureteropelvic junction obstruction: morphological and clinical studies},
  author={Ping Zhang and Craig A. Peters and Seymour Rosen},
  journal={Pediatric Nephrology},
This study included 27 patients with ureteropelvic (UPJ) obstruction. Both renal parenchyma and the junctional abnormality were examined and correlated with clinical findings. Renal biopsies were categorized into grades 1–4. Those with normal or minimal findings (grade 1 and 2, respectively) had excellent renal function as assessed by radionuclide studies. Those with grade 4 had severe histological abnormalities associated with poor renal function. Grade 3 renal changes were seen in patients… CONTINUE READING
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Abnor - mal innervation and altered nerve growth factor messenger ribonucleic acid expression in ureteropelvic junction obstruction

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