Ureidosuccinic acid uptake in yeast and some aspects of its regulation.

@article{Drillien1972UreidosuccinicAU,
  title={Ureidosuccinic acid uptake in yeast and some aspects of its regulation.},
  author={Robert Drillien and François Lacroute},
  journal={Journal of bacteriology},
  year={1972},
  volume={109 1},
  pages={203-8}
}
Ureidosuccinic acid (USA) is an intermediary product in pyrimidine biosynthesis. When proline was the sole nitrogen source, USA uptake occurred; however, when ammonium sulfate or glutamic acid was the nitrogen source, uptake was inhibited. Thus, a ura2 strain which does not synthesize USA would not grow when this substance was supplied on an ammonium sulfate or glutamic acid medium. Mutants are described in which uptake was constitutive on such a medium. Permeaseless mutants for USA have been… CONTINUE READING

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