[Urea sensor for the continuous ammonium-selective enzymatic process control of the artificial kidney].

Abstract

Presented is a flow-through method for continuous ammonium-selective enzymatic monitoring of the artificial kidney by means of a bioelectrochemical urea electrode. The urea is converted in an enzyme membrane by covalently bound urease and the ammonium ions are detected by a Nonactin-PVC-membrane. In addition to detailed data from the oxygen-independent solid-state contact sensor, curves are obtained on-line from the patient during the haemodialysis session. The advantages of the method are described in detail. Furthermore, the urea sensor can be used for measurements in heparinized blood.

Cite this paper

@article{Schindler1994UreaSF, title={[Urea sensor for the continuous ammonium-selective enzymatic process control of the artificial kidney].}, author={J. G. Schindler and Matthew Schindler and K Herna and E. Reisinger and B. Burk and Ulrike Kuhlmann and John Knaack and Brigitta Schmidt and Heidrun Lange}, journal={European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies}, year={1994}, volume={32 3}, pages={145-52} }