Urea kinetic and middle molecule approaches to assessing the adequacy of hemodialysis and CAPD.

@article{Keshaviah1993UreaKA,
  title={Urea kinetic and middle molecule approaches to assessing the adequacy of hemodialysis and CAPD.},
  author={Prakash R. Keshaviah},
  journal={Kidney international. Supplement},
  year={1993},
  volume={40},
  pages={S28-38}
}
The historical bases and implications of the urea kinetic and middle molecule approaches to assessing the adequacy of hemodialysis and continuous ambulatory peritoneal dialysis (CAPD) are reviewed in this paper. A critical reappraisal of the findings of the National Cooperative Dialysis Study (NCDS) demonstrates the importance of small solute removal on clinical outcomes of morbidity and mortality in the hemodialysis setting. The applicability of these results to CAPD is examined in the light… CONTINUE READING